Safety of Re-dosing Nirsevimab Prior to RSV Season 2 in Children With Heart or Lung Disease
JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY(2023)
Abstract
In children with congenital heart disease and/or chronic lung disease entering their second respiratory syncytial virus (RSV) season, 200 mg nirsevimab had a similar safety profile to that of palivizumab and resulted in nirsevimab serum exposures associated with efficacy in healthy infants, supporting efficacy in this population at risk of severe RSV disease.
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Key words
monoclonal antibody,nirsevimab,pharmacokinetics,palivizumab,respiratory syncytial virus
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