The role of protein kinase R in placental inflammation, mtUPR and apoptosis.

Umut Kerem Kolac,Gizem Donmez Yalcin,Ramazan Karayel,Abdullah Yalcin

Placenta（2023）

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摘要

Our results showed that LPS and Poly I:C administration stimulated PKR in BeWo cells in vitro. Furthermore, PKR activation is correlated with the levels of proteins involved in mitochondrial homeostasis and apoptosis. Our findings will contribute to understanding the role of PKR activation in placental inflammation and related diseases.

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placental inflammation,protein kinase,apoptosis

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