Haloperidol versus Second-generation Antipsychotics on the cognitive performance of individuals with schizophrenia and related disorders: pairwise meta-analysis of randomized controlled trials.

Daniel Prates Baldeza, Tais Boeira Biazus,Francisco Diego Rabelo-da-Ponte,Guilherme Pedro Nogaro, Dayane Santos Martins, João Pedro Soledade Signori, Vanessa Gnielka,Ives Cavalcante Passos,Letícia Sanguinetti Czepielewski,Maurício Kunz

Trends in psychiatry and psychotherapy（2023）

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摘要

Haloperidol had poorer performance in global cognition and in some cognitive domains, but with small effect sizes. Therefore, it was not possible to conclude that haloperidol is certainly worse than SGAs in the long-term cognitive management of schizophrenia.

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