Clinical significance of L1CAM expression in metastatic tubo-ovarian high-grade serous carcinoma

Margarida Varela dos Santos,Arild Holth,Kristina Lindemann,Anne Cathrine Staff,Ben Davidson

Gynecologic Oncology（2023）

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摘要

•L1CAM is overexpressed in HGSC effusions compared to surgical specimens.•L1CAM expression in surgical specimens is significantly related to primary (intrinsic) chemoresistance.•L1CAM overexpression in effusions is associated with shorter overall survival.

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关键词

l1cam expression,carcinoma,clinical significance,tubo-ovarian,high-grade

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