Gene-network analysis predicts clinical response to immunotherapy in patients affected by NSCLC

Federico Cucchiara,Stefania Crucitta,Iacopo Petrini,Diego de Miguel Perez,Martina Ruglioni,Eleonora Pardini,Christian Rolfo,Romano Danesi,Marzia Del Re

Lung Cancer（2023）

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摘要

•Gene-network analysis represents a potential biomarker of response to therapies.•Mutations in gene signalling pathways positively predict ICI-treated advanced NSCLC.•Gene networks could be valuable for personalizing treatment decisions.

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