SARS-CoV-2 antibody response duration and neutralization following natural infection

Christopher W Dukes, Renata AM Rossetti,Jonathan A Hensel,Sebastian Snedal,Christopher L Cubitt,Michael J Schell,Martha Abrahamsen,Kimberly Isaacs-Soriano,Kayoko Kennedy,Leslie N Mangual,Junmin Whiting, Veronica Martinez-Brockhus,Jessica Y Islam,Julie Rathwell,Matthew Beatty,Amy M Hall,Daniel Abate-Daga,Anna R Giuliano,Shari Pilon-Thomas

Journal of Clinical Virology Plus（2023）

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摘要

•83.2% of COVID-19 convalescent participants positive for neutralizing antibodies.•Positive association of neutralization capacity with higher antibody levels.•Older participants had higher antibody levels and neutralization capacity.•Ethnicity, heart, and autoimmune disease associated with increased antibody levels.•Antibody levels drop for unvaccinated participants at 3-month follow-up.

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natural infection,sars-cov

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