Common comorbid and secondary conditions leading to hospitalization in multiple sclerosis patients in the United States

•Patients with MS are admitted into hospital at a younger age, are hospitalized longer and consume more Medicare resources than the similar patients without MS in the general population.•The majority of all MS hospitalizations occurred among persons in the 30–69-year age bracket.•Infections account for a large proportion of MS-associated hospitalizations, from young adulthood onward.•After adjusting for age and gender, patients with a MS had significantly greater length of hospital stays than non-MS patients.