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Hypoglycemic effect and active ingredients screening of Isodon Japonicus based on network pharmacology and experimental validation

Xiao Xian,Li Chunyan, Wang Canyu, Zhu Huiqing,Song Liaofan,Liu Xiaolong, Lu Yusi, Yang Pengfei, Zhang Nan,Xue Jintao

Arabian Journal of Chemistry（2023）

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Abstract
•The ingredient-target-pathway relationship was studied by network pharmacology.•11 hypoglycemic components, 12 targets and 130 pathways were found.•Cell test and animal experiments were used to confirm the hypoglycemic effects.
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Key words
isodon japonicus,hypoglycemic effect,active ingredients screening,network pharmacology
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