Improved Outcome for ALL by Prolonging Therapy for IKZF1 Deletion and Decreasing Therapy for Other Risk Groups.

Rob Pieters,Hester de Groot-Kruseman,Marta Fiocco,Femke Verwer,Merian Van Overveld,Edwin Sonneveld, Vincent van der Velden, H Berna Beverloo, Marc Bierings,Natasja Dors,Valérie de Haas,Peter Hoogerbrugge,Inge Van der Sluis,Wim Tissing,Margreet Veening,Judith Boer,Monique Den Boer

Journal of clinical oncology : official journal of the American Society of Clinical Oncology（2023）

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Abstract

Children with del ALL seem to benefit from prolonged maintenance therapy. Chemotherapy was successfully reduced for patients with , DS, and PPR ALL. It has to be noted that these results were obtained in a nonrandomized study using a historical control group.

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