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Baseline serum HBV RNA is associated with the risk of hepatitis flare after stopping nucleoside analog therapy in HBeAg-negative participants.

Alexander J Thompson,Kathy Jackson,Sara Bonanzinga,Sam A L Hall,Simon Hume,Gareth S Burns,Vijaya Sundararajan,Dilip Ratnam,Miriam T Levy,John Lubel,Amanda J Nicoll,Simone I Strasser,William Sievert,Paul V Desmond,Meng C Ngu,Marie Sinclair,Christopher Meredith,Gail Matthews,Peter A Revill,Margaret Littlejohn,D Scott Bowden,Jesse A Canchola,Jason Torres,Philip Siew, Jasmin Lau,Benjamin La Brot,Alison Kuchta,Kumar Visvanathan

Hepatology communications（2023）

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Abstract
Serum HBV RNA may be a useful biomarker for guiding clinical decision-making before stopping nucleot(s)ide analog therapy. Baseline HBV RNA and HBsAg levels are associated with the risk of clinical relapse, hepatitis flare, and disease remission off-treatment.
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Key words
baseline serum hbv rna,hepatitis flare,nucleoside analog therapy,hbeag-negative
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