Tandem Baeyer-Villiger/Wittig/oxa-Michael addition: One-step to 5-substituted y-lactones

Tetrahedron Letters(2023)

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摘要
The results reported in this study provide a practical protocol for the construction, in one single step of synthetically important y-lactones in good yields starting from a-hydroxy cyclobutanone, H2O2 and sev-eral stabilized phosphonium ylides. Our synthetic strategy relies on a tandem Baeyer-Villiger oxidation/ Wittig reaction/oxa-Michael addition. & COPY; 2023 Elsevier Ltd. All rights reserved.
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关键词
y-Lactones,Baeyer-Villiger,Strained rings,Tandem reactions
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