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Correlation of Reduced PTGER3 Expression with Prognosis and Immune Infiltration in Clear Cell Renal Carcinoma.

Ke Yang, Bin Hu,Guohua Zhu,Dongbo Yuan,Wei Wang,Hao Su,Heng Liu,Jianguo Zhu

Archivos espanoles de urologia（2023）

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Abstract
The expression of PTGER3 was found to be diminished in KIRC in comparison to paracancerous tissue. This observation exhibited a correlation with both prognosis and immune cell infiltration. As a result, our findings suggest that PTGER3 could be considered a promising biomarker to forecast KIRC prognosis and as a possible target for immunotherapy.
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Key words
clear cell renal carcinoma, prostaglandin E2 receptor 3, PTGER3, TCGA, bioinformatics
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