Histopathological and Immunohistochemical Prognostic Factors in High-Grade Non-Endometrioid Carcinomas of the Endometrium (HG-NECs): Is It Possible to Identify Subgroups at Increased Risk?

Michele Paudice,Chiara Maria Biatta,Giulia Scaglione, Alessia Parodi,Serafina Mammoliti,Melita Moioli,Maria Grazia Centurioni,Fabio Barra,Simone Ferrero,Franco De Cian,Katia Mazzocco,Valerio Gaetano Vellone

Diagnostics (Basel, Switzerland)（2023）

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摘要

HG-NEC represents a heterogeneous group of endometrial aggressive neoplasms with a worrisome prognosis, often at an advanced stage at presentation. Bcl-2 and PR may represent promising markers to identify a subgroup of patients having an even worse prognosis requiring a careful and close follow-up.

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关键词

endometrial carcinoma, immunohistochemistry, prognosis

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