Secondary dengue serotype 1 infection causing dengue shock syndrome with rhombencephalitis and bleeding associated with refractory thrombocytopenia: A case report.

Manoon Surabotsophon,Poonsak Laohachavalit,Sunsern Ponglikitmongkol, Suporn Chuncharunee, Thanwa Sudsang,Vipa Thanachartwet,Duangjai Sahassananda,Taweewun Hunsawong,Chonticha Klungthong,Stefan Fernandez,Siripen Kalayanarooj,Varunee Desakorn, Suthee Leelasetakul

Heliyon（2023）

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摘要

Dengue is a potential cause of rhombencephalitis. Dengue-associated rhombencephalitis develops during the critical phase, with only partial neurological recovery. However, severe bleeding and refractory thrombocytopenia were also observed during the recovery phase. Methylprednisolone with a thrombopoietin receptor agonist could be an effective treatment for increasing platelet count and stopping bleeding in dengue.

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关键词

Case report,Dengue,Encephalitis,Refractory thrombocytopenia,Rhombencephalitis

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