Platelet-derived microparticles provoke chronic lymphocytic leukemia malignancy through metabolic reprogramming.

Ehsan Gharib,Vanessa Veilleux,Luc H Boudreau,Nicolas Pichaud,Gilles A Robichaud

Frontiers in immunology（2023）

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摘要

Altogether, these findings depict a new platelet-mediated pathway of cancer pathogenesis. We also highlight the impact of PMPs in CLL metabolic reprogramming and disease progression.

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关键词

platelets, microvesicles, leukemia, microparticles, extracellular vesicles, mitochondria

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