Faecal microbiota transplantation from young rats attenuates age-related sarcopenia revealed by multiomics analysis.

Xiaoxing Mo,Lihui Shen,Ruijie Cheng,Pei Wang, Lin Wen,Yunhong Sun,Qiang Wang,Juan Chen, Shan Lin,Yuxiao Liao,Wei Yang,Hong Yan,Liegang Liu

Journal of cachexia, sarcopenia and muscle（2023）

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摘要

yFMT could reshape the dysbiosis of gut microbiota and metabolites, maintain gut barrier integrity, and improve muscle mitochondrial dysfunction, eventually alleviating sarcopenia in aged rats. yFMT might be a new therapeutic strategy for age-related sarcopenia.

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关键词

Fecal microbiota transplantation, Gut microbiota, Metabolites, Mitochondrial dysfunction, Muscle, Sarcopenia

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