Verbalide A~F: new phthalide derivatives from the endophytic fungus Preussia sp. CPCC 400972

Ran Zhang,Yujia Wang,Guowei Cai,Juxian Wang,Jianyuan Zhao,Jinglin Bai,Tao Zhang,Shan Cen,Wenni He,Liyan Yu

The Journal of Antibiotics（2023）

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摘要

There are six new phthalide derivatives Verbalide A ~ F ( 1 – 6 ) together with another known derivative ( 7 ) isolated from the endophytic fungus Preussia sp. CPCC 400972. Their structures were established by comprehensive spectroscopic analyses, including NMR and HRESIMS. In addition, compounds 1 – 7 exhibited excellent inhibitory effect against influenza A virus.

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new phthalide derivatives,endophytic fungus preussia sp

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