从中医痰湿相关理论探讨调控自噬干预肥胖的理论依据
Chinese Archives of Traditional Chinese Medicine（2023）
Abstract
通过阅读文献,以细胞自噬与肥胖炎症状态、痰湿困脾与肥胖病机、自噬异常与痰湿困脾,以及化痰祛湿健脾法与代谢炎症性相关疾病等为关键词探讨肥胖的形成与干预机制,认为肥胖的形成与细胞自噬异常所致的慢性炎症状态密切相关,提出肥胖的病机关键为痰湿困脾,并深入阐析了细胞自噬异常与痰湿困脾的内在关联,明确了从化痰祛湿健脾入手可能是调控细胞自噬改善肥胖等相关代谢性疾病的有效手段.这为从细胞自噬的角度阐明肥胖痰湿病机及干预治疗提供了理论依据.
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Key words
obesity,autophagy,phlegm-dampness trapping spleen,mechanisms
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