PRAME expression in cutaneous melanoma does not correlate with disease-specific survival.

Ourania Parra,Weijie Ma,Zhongze Li,Bryan N Coffing,Konstantinos Linos,Robert E LeBlanc,Shabnam Momtahen,Aravindhan Sriharan,Jeffrey M Cloutier,Wendy A Wells,Shaofeng Yan

Journal of cutaneous pathology（2023）

Cited 1|Views8

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Abstract

Ki-67 is an independent prognostic marker; although increased PRAME expression correlates with the Ki-67 proliferation index and mitotic rate, PRAME is not an independent prognostic marker for cutaneous melanoma. PRAME and Ki-67 are useful ancillary tools for distinguishing benign from malignant melanocytic lesions.

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Key words

benign nevus, cutaneous malignant melanoma, Ki-67, PRAME, prognosis, survival, tissue, microarray

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