Reconsidering the role of protein glycation in disease
Nature chemical biology（2023）
Abstract
Protein glycation has long-been considered a toxic consequence of carbohydrate metabolism. Yet recent evidence demonstrates tight regulation for these non-enzymatic post-translational modifications, pointing to a broader role in cell biology rather than simply serving as a biomarker for toxicity.
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Key words
Chemical tools,Histone post-translational modifications,Metabolism,Post-translational modifications,Chemistry/Food Science,general,Biochemical Engineering,Biochemistry,Cell Biology,Bioorganic Chemistry
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