Enhanced inflammasome-mediated inflammation and impaired autophagy in peripheral blood mononuclear cells is associated with non-alcoholic fatty liver disease severity.

Life sciences(2023)

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Abstract
Present data provide mechanistic evidence of impaired autophagy and intracellular ROS triggering inflammasome activation in PBMCs which could potentially exacerbate NAFLD severity.
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Key words
impaired autophagy,inflammation,liver disease,peripheral blood mononuclear cells,inflammasome-mediated,non-alcoholic
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