SARS-CoV-2 virologic rebound with nirmatrelvir-ritonavir therapy.

medRxiv : the preprint server for health sciences(2023)

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摘要
Virologic rebound occurred in approximately one in five people taking nirmatrelvir-ritonavir and often occurred without worsening symptoms. Because it is associated with replication-competent viral shedding, close monitoring and potential isolation of those who rebound should be considered.
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