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A Novel Gain-of-function PIP4K2A Mutation Elevates the Expression of Β-Globin and Aggravates the Severity of Α-Thalassemia

Yanxia Zhang,Hongting Xie,Guanxia Liang,Yunrong Qin, Xiaofeng Wei,Sisi Ning,Yi Liang,Xiongda Liang,Yuling Xie,Zezhang Lin,Dina Zhu,Jiaqiong Lin,Fu Xiong,Xiangming Xu,Xuan Shang

BRITISH JOURNAL OF HAEMATOLOGY（2023）

Cited 1|Views38
Key words
erythroid differentiation,gain-of-function mutation,Hb H disease,PIP4K2A,terminal enucleation,beta-globin
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