Evaluation of Monkeypox- and Vaccinia virus-neutralizing antibodies in human serum samples after vaccination and natural infection.

Alessandro Manenti,Niccolò Solfanelli,Paolo Cantaloni,Livia Mazzini,Margherita Leonardi,Linda Benincasa,Giulia Piccini,Serena Marchi,Martina Boncioli, Chiara Spertilli Raffaelli, Danilo Tacconi,Giada Mattiuzzo,Otfried Kistner,Emanuele Montomoli,Claudia Maria Trombetta

Frontiers in public health（2023）

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摘要

The results of the present study confirm the presence and cross-reactivity of antibodies elicited by vaccinia-based vaccines, which proved able to neutralize the Monkeypox virus in the presence of an external source of complement.

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关键词

humoral immunity, neutralization, Monkeypox virus, vaccinia virus, epidemiology

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