Preoperative immunological plasma markers TRAIL, CSF1 and TIE2 predict survival after resection for biliary tract cancer.

Hannes Jansson,Martin Cornillet,Dan Sun,Iva Filipovic,Christian Sturesson,Colm J O'Rourke,Jesper B Andersen,Niklas K Björkström,Ernesto Sparrelid

Frontiers in oncology（2023）

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摘要

In conclusion, three preoperative immunological plasma markers were prognostic for survival after surgery for BTC, providing good discrimination, even compared to postoperative pathology. TRAIL and CSF1, prognostic factors in intrahepatic cholangiocarcinoma, showed marked differences in expression and activity between intra- and peritumoral immune cells.

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关键词

cholangiocarcinoma (CCA), gallbladder cancer (GBC), prognostic biomarkers, tumor associated macrophage (TAM), biliary tract cancer (BTC)

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