Extracellular aaRSs drive autoimmune and inflammatory responses in rheumatoid arthritis via the release of cytokines and PAD4.
Annals of the rheumatic diseases（2023）
摘要
Our findings uncovered the significant role of aaRSs as a novel alarmin in RA pathogenesis, indicating that their blocking agents are potent antirheumatic drugs.
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关键词
Arthritis, Rheumatoid, Cytokines, Inflammation, Autoimmunity
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