Antithrombotic therapy in antiphospholipid syndrome with arterial thrombosis: a systematic review and network meta-analysis.

Tanawat Attachaipanich, Aimpat Aungsusiripong,Pokpong Piriyakhuntorn,Sasinee Hantrakool,Ekarat Rattarittamrong,Thanawat Rattanathammethee,Adisak Tantiworawit,Lalita Norasetthada,Chatree Chai-Adisaksopha

Frontiers in medicine（2023）

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摘要

Based on this NMA, the combination of warfarin and antiplatelet therapy appears to be an effective approach in preventing recurrent overall thrombosis in APS patients with a history of arterial thrombosis. While DAPT may also show promise in preventing recurrent arterial thrombosis, further studies are needed to confirm its efficacy. Conversely, the use of DOACs was found to significantly increase the risk of recurrent arterial thrombosis.

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关键词

anticoagulant, antiphospholipid syndrome, network meta-analysis, platelet aggregation inhibitors, thrombosis

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