Accurate method for value assignment of carcinoembryonic antigen reference materials.
Journal of clinical laboratory analysis(2023)
摘要
The BCCL candidate RMs (C2-C5) for CEA were commutable among all immunoassays. WHO 73/601 RMs diluted in a PBS buffer matrix were selected as common calibrators for five immunoassays, which reduced bias, thereby effectively improving the harmonization of CEA detection; therefore, they could be used to assign values to CEA candidate RMs developed by BCCL. Our findings promote the harmonization of CEA detection in immunoassays.
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关键词
carcinoembryonic antigen, commutability, comparability, reference material
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