Renin Cell Development: Insights From Chromatin Accessibility and Single-Cell Transcriptomics.

HomeCirculation ResearchAhead of PrintRenin Cell Development: Insights From Chromatin Accessibility and Single-Cell Transcriptomics Free AccessResearch ArticlePDF/EPUBAboutView PDFSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toFree AccessResearch ArticlePDF/EPUBRenin Cell Development: Insights From Chromatin Accessibility and Single-Cell Transcriptomics Alexandre G. Martini, Jason P. Smith, Silvia Medrano, Gal Finer, Nathan C. Sheffield, Maria Luisa S. Sequeira-Lopez and R. Ariel Gomez Alexandre G. MartiniAlexandre G. Martini Departments of Pediatrics, Child Health Research Center, University of Virginia, Charlottesville. (A.G.M., J.P.S., S.M., M.L.S.S.-L., R.A.G.) *A. Martini and J. Smith contributed equally. Search for more papers by this author , Jason P. SmithJason P. Smith https://orcid.org/0000-0002-2688-0988 Departments of Pediatrics, Child Health Research Center, University of Virginia, Charlottesville. (A.G.M., J.P.S., S.M., M.L.S.S.-L., R.A.G.) *A. Martini and J. Smith contributed equally. Search for more papers by this author , Silvia MedranoSilvia Medrano https://orcid.org/0000-0002-8516-0788 Departments of Pediatrics, Child Health Research Center, University of Virginia, Charlottesville. (A.G.M., J.P.S., S.M., M.L.S.S.-L., R.A.G.) Search for more papers by this author , Gal FinerGal Finer https://orcid.org/0000-0002-1488-9985 Division of Nephrology, Ann and Robert H. Lurie Children’s Hospital of Chicago, IL (G.F.). Search for more papers by this author , Nathan C. SheffieldNathan C. Sheffield https://orcid.org/0000-0001-5643-4068 Center for Public Health Genomics, University of Virginia, Charlottesville. (N.C.S.) Departments of Public Health Sciences, University of Virginia, Charlottesville. (N.C.S.) Biomedical Engineering, University of Virginia, Charlottesville. (N.C.S.) Biochemistry and Molecular Genetics, University of Virginia, Charlottesville. (N.C.S.) Search for more papers by this author , Maria Luisa S. Sequeira-LopezMaria Luisa S. Sequeira-Lopez Maria Luisa S. Sequeira-Lopez, MD, 409 Ln Rd, Rooms 2001, 2006, and 2010, Charlottesville, VA 22908. Email E-mail Address: [email protected] https://orcid.org/0000-0002-4459-7940 Departments of Pediatrics, Child Health Research Center, University of Virginia, Charlottesville. (A.G.M., J.P.S., S.M., M.L.S.S.-L., R.A.G.) Search for more papers by this author and R. Ariel GomezR. Ariel Gomez Correspondence to: R. Ariel Gomez, MD, 409 Ln Rd, Rooms 2001, 2006, and 2010, Charlottesville, VA 22908. Email E-mail Address: [email protected] https://orcid.org/0000-0002-5124-8255 Departments of Pediatrics, Child Health Research Center, University of Virginia, Charlottesville. (A.G.M., J.P.S., S.M., M.L.S.S.-L., R.A.G.) Search for more papers by this author Originally published3 Jul 2023https://doi.org/10.1161/CIRCRESAHA.123.322827Circulation Research. 2023;0Footnotes*A. Martini and J. Smith contributed equally.For Sources of Funding and Disclosures, see page XXX.Correspondence to: R. Ariel Gomez, MD, 409 Ln Rd, Rooms 2001, 2006, and 2010, Charlottesville, VA 22908. Email [email protected]orgMaria Luisa S. Sequeira-Lopez, MD, 409 Ln Rd, Rooms 2001, 2006, and 2010, Charlottesville, VA 22908. Email [email protected]org eLetters(0)eLetters should relate to an article recently published in the journal and are not a forum for providing unpublished data. Comments are reviewed for appropriate use of tone and language. Comments are not peer-reviewed. Acceptable comments are posted to the journal website only. Comments are not published in an issue and are not indexed in PubMed. Comments should be no longer than 500 words and will only be posted online. References are limited to 10. Authors of the article cited in the comment will be invited to reply, as appropriate.Comments and feedback on AHA/ASA Scientific Statements and Guidelines should be directed to the AHA/ASA Manuscript Oversight Committee via its Correspondence page.Sign In to Submit a Response to This Article Previous Back to top Next FiguresReferencesRelatedDetails Advertisement Article InformationMetrics © 2023 American Heart Association, Inc.https://doi.org/10.1161/CIRCRESAHA.123.322827PMID: 37395102 Originally publishedJuly 3, 2023 Keywordschromatintranscriptomeperfusionreninmesangial cellspericytesPDF download Advertisement SubjectsEpigeneticsGene Expression and RegulationHypertensionOmics