[GENOTYPE-PHENOTYPE CORRELATIONS BY SPECIFIC FOUNDER VARIANTS IN BRCA IN ISRAELI WOMEN].

Rachel Michaelson-Cohen,Yael Laitman,Inbal Kedar,Hagit Baris-Feldman,Orit Reish,Sari Lieberman,Rinat Bernstein-Molho,Yael Goldberg,Gili Reznick Levi,Ruth Gershoni,Uzi Beller,Ephrat Levy-Lahad, Raphael Catan,Eitan Friedman

Harefuah（2023）

引用 0|浏览15

暂无评分

摘要

In our population, similar to others, BRCA1 carriers have higher cancer rates and earlier age at diagnosis compared with BRCA2 carriers. The two recurring BRCA1 PVs have different risks: 5382insC carriers had more BC; 185delAG carriers had more OC. Risk-reducing measures should be based on variant-specific cancer risk.

查看译文

关键词

specific founder variants,brca,[genotype-phenotype

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要