Antidepressant-like effects of L-menthol mediated by alleviating neuroinflammation and upregulating the BDNF/TrkB signaling pathway in subchronically lipopolysaccharide-exposed mice.
Brain research（2023）
Abstract
•Acute antidepressant-like effects of LM were validated through different mouse models.•A modified LPS-induced depression model was subchronically established in the study.•Subchronic antidepressant-like effects of LM were confirmed in the modified model.•Alleviation of neuroinflammation and upregulation of BDNF/TrkB pathway mediated the procedure.
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