Islet autoimmunity and type 1 diabetes associated with enterovirus infections.

Although it is reasonable for physicians to be sceptical of new ideas, innovation often emerges from situations in which results carefully obtained do not fit within the accepted paradigms. 1 The Nobel PrizeStanley B Prusiner: Biographical. https://www.nobelprize.org/prizes/medicine/1997/prusiner/biographical/Date: May 10, 2023 Date accessed: May 17, 2023 Google Scholar Enteroviruses and risk of islet autoimmunity or type 1 diabetes: systematic review and meta-analysis of controlled observational studies detecting viral nucleic acids and proteinsThese findings highlight the association between enteroviruses and islet autoimmunity or type 1 diabetes. Our data strengthen the rationale for vaccine development targeting diabetogenic enterovirus types, particularly those within Enterovirus B. Prospective studies of early life are needed to elucidate the role of enterovirus timing, type, and infection duration on the initiation of islet autoimmunity and the progression to type 1 diabetes. Full-Text PDF