Spontaneous coronary artery dissection in women with acute myocardial infarction: is there a new role for autoimmunity?

Giovanni Civieri,Marta Vadori,Giulia Masiero,Laura Iop,Donatella Tansella,Valeria Pergola,Emanuele Cozzi,Sabino Iliceto,Francesco Tona

European heart journal. Acute cardiovascular care（2023）

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摘要

AT1R-AAs and ETAR-AAs seropositivity is significantly higher in SCAD women with myocardial infarction than in healthy women or female patients with STEMI. Our findings, corroborated by previous data in the literature and biological plausibility, suggest a possible role for AT1R-AAs and ETAR-AAs in the pathophysiology of SCAD in women with acute myocardial infarction and should warrant further studies with larger sample sizes.

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关键词

Spontaneous coronary artery dissection, Autoimmunity, Autoantibodies, Angiotensin, Endothelin, Pathophysiology

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