Exosomes released from macrophages infected with Talaromyces marneffei activate the innate immune responses and decrease the replication.
Immunity, inflammation and disease(2023)
Abstract
Our studies are the first to demonstrate that exosomes isolated from T. marneffei-infected macrophages can modulate the immune system to control inflammation, and we hypothesize that exosomes play significant roles in activation of ERK1/2 and autophagy, the replication of T. marneffei and cytokine production during T. marneffei infection.
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Key words
macrophages,innate immune responses,immune responses
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