Biosynthesis of Gold Nanoparticles Using Quince Seed Water Extract and Investigation of Their Anticancer Effect Against Cancer Cell Lines

IEEE TRANSACTIONS ON NANOBIOSCIENCE(2024)

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摘要
In this study, gold nanoparticles (Au-NPs) were synthesized using HAuCl4 and quince seed mucilage (QSM) extract, which was characterized by conventional methods including Fourier transforms electron microscopy (FTIR), UV-Visible spectroscopy (UV-Vis), Field emission electron microscopy (FESEM), Transmission electron microscopy (TEM), Dynamic light spectroscopy (DLS), and Zeta-potential. The QSM acted as reductant and stabilizing agents simultaneously. The NP's anticancer activity was also investigated against osteosarcoma cell lines (MG-63), which showed an IC50 of $317 \mu \text{g}$ /mL.
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关键词
Nanoparticles,Seeds (agriculture),Gold,Absorption,Transmission electron microscopy,Cancer,Nanobioscience,Gold nanoparticles,quince seed mucilage extract,anticancer,biosynthesis
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