Targeting CHAF1B Enhances IFN Activity against Myeloproliferative Neoplasm Cells.

Diana Saleiro,Ewa M Kosciuczuk,Mariafausta Fischietti,Ricardo E Perez,G Sohae Yang,Frank Eckerdt,Elspeth M Beauchamp,Ye Hou,Qixuan Wang,Rona Singer Weinberg,Eleanor N Fish,Feng Yue,Ronald Hoffman,Leonidas C Platanias

Cancer research communications（2023）

引用 0|浏览4

暂无评分

摘要

Our findings raise the potential for clinical development of drugs targeting CHAF1B to enhance IFN antitumor responses in the treatment of patients with MPN and should have important clinical translational implications for the treatment of MPN and possibly in other malignancies.

查看译文

关键词

chaf1b enhances ifn activity,myeloproliferative neoplasm cells

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要