Chlorogenic Acid Induced Neuroblastoma Cells Differentiation via the ACAT1-TPK1-PDH Pathway.

Shen You,Ming-Jin Wang,Zhen-Yan Hou,Wei-Da Wang,Ting-Ting Du,Ni-Na Xue,Ming Ji,Xiao-Guang Chen

Pharmaceuticals (Basel, Switzerland)（2023）

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摘要

These results provide evidence that CHA shows good antitumor activity against neuroblastoma via the induction of differentiation, by which the ACAT1-TPK1-PDH pathway is involved. CHA is a potential drug candidate for neuroblastoma therapy.

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关键词

neuroblastoma, chlorogenic acid, differentiation, acetyl-CoA acetyltransferase, thiamine

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