Extracellular Vesicles as Drug Transporters.

Monika Nowak, Julia Górczyńska,Katarzyna Kołodzińska, Jakub Rubin,Anna Choromańska

International journal of molecular sciences(2023)

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Abstract
Extracellular vesicles (EVs) are lipid bilayer-delimited particles. According to their size and synthesis pathway, EVs can be classified into exosomes, ectosomes (microvesicles), and apoptotic bodies. Extracellular vesicles are of great interest to the scientific community due to their role in cell-to-cell communication and their drug-carrying abilities. The study aims to show opportunities for the application of EVs as drug transporters by considering techniques applicable for loading EVs, current limitations, and the uniqueness of this idea compared to other drug transporters. In addition, EVs have therapeutic potential in anticancer therapy (especially in glioblastoma, pancreatic cancer, and breast cancer).
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Key words
extracellular vesicles, drug delivery, nanomedicine, engineering, cancer treatment
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