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Effects of soft tissue sarcoma and doxorubicin on bone metabolism in mice

Fumihito Kasama,Hiroyuki Tsuchie,Hiroyuki Nagasawa,Yuji Kasukawa,Koji Nozaka,Ryo Shoji,Shun Igarashi,Shuntaro Harata,Naohisa Miyakoshi

In vivo (Athens, Greece)（2023）

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Abstract
The use of doxorubicin alone worsened the cortical bone structure; however, the presence of both soft-tissue sarcoma and doxorubicin use worsened both cortical and trabecular bone structures from an early stage.
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Key words
Soft-tissue sarcoma, doxorubicin, osteoporosis
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