Post-transplantation Cyclophosphamide-based Graft-versus-host-disease Prophylaxis Compared to Methotrexate-cyclosporine a in Matched-related Allogeneic Hematopoietic Stem Cell Transplantation.

Mohamed T Shouman, Osman M Mansour,Mosaad M El Gammal,Raafat M Abdel-Fattah,Mohamed A Samra,Alaa M Elhaddad, Mohamed A Maher,Hossam K Mahmoud

Hematology/oncology and stem cell therapy（2023）

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Abstract

PTCy-based GVHD prophylaxis in MRD transplant is feasible and leads to lower chronic GVHD rates without causing a significantly different risk of relapse or survival than MTX/CsA. More extensive studies are needed to confirm our results.

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Key words

cyclophosphamide,post-transplantation,graft-versus-host-disease,methotrexate-cyclosporine

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