Deep phenotyping of pubertal development in Norwegian children: the Bergen Growth Study 2.

Petur B Juliusson,Ingvild S Bruserud,Ninnie Helen Bakken Oehme,Andre Madsen,Ingvild H Forthun,Melissa Balthasar,Karen Rosendahl,Kristin Viste,Astanand Jugessur,Lawrence M Schell,Robert Bjerknes,Mathieu Roelants

Annals of human biology（2023）

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摘要

Ultrasound-based assessments of puberty provided novel references for breast developmental stages and enabled the measurement of testicular volume on a continuous scale. Endocrine -scores allowed for an intuitive interpretation of changing hormonal levels during puberty on a quantitative scale, which, in turn, provides opportunities for further analysis of pubertal development using machine-learning approaches.

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关键词

bergen growth study,norwegian children,pubertal development,deep phenotyping

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