Visceral hypersensitivity induced by mild traumatic brain injury via the corticotropin-releasing hormone receptor: An animal model.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society(2023)
摘要
LISW provoked visceral hypersensitivity, small intestinal hyperpermeability, altered expression of CRFRs and changes in the microbiota, suggesting that genuine bTBI caused by LISW can induce a pathophysiology comparable to that of human IBS.
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关键词
cortico-tropine releasing hormone, intestinal permeability, irritable bowel syndrome, traumatic brain injury, visceral hypersensitivity
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