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Exploring the molecular characteristics of the malignant potential of gastric adenocarcinoma with enteroblastic differentiation.

Yong Wang,Xiyin Wei,Bin Ke,Jia Liu,Yuhong Guo,Yanxue Liu,Yongzi Chen,Tingting Ding,Yalei Wang,Bin Meng,Baocun Sun,Fenglin Zang

Histopathology（2023）

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Abstract
The HER2 /EBV /MSS/TP53 /PD-L1 profile and hepatocellular carcinoma-related pathways may be significant in the malignant potential of GAED. In addition to anti-HER2 therapy, immune check-point inhibitors may be an effective treatment option for patients with GAED.
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Key words
gastric adenocarcinoma,malignant potential,molecular characteristics,differentiation
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