Prevailing Antagonistic Risks in Pleiotropic Associations with Alzheimer's Disease and Diabetes.

Alexander M Kulminski,Fan Feng,Elena Loiko,Alireza Nazarian,Yury Loika,Irina Culminskaya

Journal of Alzheimer's disease : JAD（2023）

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摘要

This study emphasizes differences and similarities in the heterogeneous genetic architectures of AD and DM, which may differentiate the pathogenic mechanisms of these diseases.

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关键词

Alzheimer's disease, apolipoprotein E gene, diabetes, major histocompatibility complex, pleiotropy

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