Multi-stage image registration based on list-mode proton radiographies for small animal proton irradiation: A simulation study

Prasannakumar Palaniappan, Yana Knudsen,Sebastian Meyer,Chiara Gianoli, Katrin Schnürle,Matthias Würl,Jonathan Bortfeldt,Katia Parodi,Marco Riboldi

Zeitschrift fur medizinische Physik（2023）

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摘要

We present a multi-stage and multi-resolution deformable image registration framework for image-guidance at a small animal proton irradiation platform. The framework is based on list-mode proton radiographies acquired at different angles, which are used to deform a 3D treatment planning CT relying on normalized mutual information (NMI) or root mean square error (RMSE) in the projection domain.

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关键词

Image-guidance,Image Registration,Small animal proton irradiation,Pre-clinical,Proton radiographies

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