Utility of TRPS1 immunohistochemistry in confirming breast carcinoma: Emphasis on staining in triple-negative breast cancers and gynecologic tumors.

Rayan Rammal,Kanika Goel,Esther Elishaev,T Rinda Soong,Mirka W Jones,Chengquan Zhao,Beth Z Clark,Gloria J Carter,Jing Yu,Jeffrey L Fine,Tatiana M Villatoro,Lauren Skvarca,Lakshmi Harinath,Rohit Bhargava

American journal of clinical pathology（2023）

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摘要

TRPS1 stains approximately 90% of breast carcinomas but also up to 71% of endometrial carcinomas, albeit with a weaker median expression. Our data show that although TRPS1 is a highly sensitive marker for TNBCs, it is not as highly specific as previously reported.

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关键词

TRPS1, immunohistochemistry, breast, TNBC, gynecologic tumors, endometrial, ovarian, vulvar

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