Histological validation of atrial structural remodelling in patients with atrial fibrillation.

Yuya Takahashi,Takanori Yamaguchi,Toyokazu Otsubo,Kana Nakashima,Kodai Shinzato,Ryosuke Osako,Shigeki Shichida,Yuki Kawano,Akira Fukui,Atsushi Kawaguchi,Shinichi Aishima,Tsunenori Saito,Naohiko Takahashi,Koichi Node

European heart journal（2023）

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摘要

Histological correlates of atrial structural remodelling were fibrosis, increased intercellular space, myofibrillar loss, and decreased nuclear density. Each histological component was defined using electron microscopy and immunohistochemistry studies.

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关键词

Atrial biopsy, Atrial fibrillation, Electroanatomic mapping, Fibrosis, Histology, Structural remodelling

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