Independent Endothelial Functions of PIEZO1 and TRPV4 in Hepatic Portal Vein and Predominance of PIEZO1 in Mechanical and Osmotic Stress

Naima Endesh,Eulashini Chuntharpursat-Bon,Charlotte Revill,Nadira Y. Yuldasheva,T. Simon Futers,Gregory Parsonage,Neil Humphreys,Antony Adamson,Lara C. Morley,Richard M. Cubbon,K. Raj Prasad,Richard Foster,Laeticia Lichtenstein,David J. Beech

LIVER INTERNATIONAL（2023）

Cited 5|Views29

Key words

arachidonic acid metabolism,calcium signalling,calcium-permeable channel,endothelial nitric oxide synthase,endothelium,hepatobiliary system,liver,mechanical force,nitric oxide,non-selective cation channel,osmolality,PIEZO channel,portal vein,transient receptor potential vanilloid 4 (TRPV4) channel,vascular relaxation,vasculature contraction,vein

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