What do you most hope spatial molecular profiling will help us understand? Part 1.

Fabian J Theis, Daniel Dar,Roser Vento-Tormo,Sanja Vicković, Linghua Wang,Luciane T Kagohara, André F Rendeiro,Johanna A Joyce

Cell systems（2023）

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摘要

A key concept in communicating results about cellular heterogeneity unearthed using single-cell genomics is the metaphor of the “cell type” understood as a cluster in gene expression space, which helps us to simplify and “understand” complex biological phenomena.

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spatial molecular profiling

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