Investigating the Expression Pattern of the SETMAR Gene Transcript Variants in Childhood Acute Leukemia: Revisiting an Old Gene.

Samaneh Boroumand-Noughabi, Ali Pashaee,Mehdi Montazer,Atefe Rahmati,Hossein Ayatollahi,Mohammad Hadi Sadeghian,Mohammad Reza Keramati

Journal of pediatric hematology/oncology（2023）

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摘要

According to the results, SETMAR showed increased expression in pediatric acute leukemia's bone marrow samples, indicating a role for this molecule in leukemia pathogenesis. As this is the first report of SETMAR expression in pediatric leukemias, further studies are needed to investigate the causality of this association.

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关键词

SETMAR, chromosomal translocation, childhood leukemia, acute myeloid leukemia, acute lymphoblastic leukemia

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